The 2025 NFL opening weekend continues with the Kansas City Chiefs and LA Chargers traveling to Brazil for a Friday night matchup. Kickoff from Arena Corinthians in São Paulo is set for 8 p.m. ET (NFL+ / YouTubeTV). Let's analyze BetMGM Sportsbook's Chiefs vs. Chargers odds and tab the 5 best prop bets to win among SportsbookWire's expert NFL picks and predictions for Week 1.

The Chiefs saw their bid for a historic 3-peat end with a 40-22 Super Bowl LIX loss to the Philadelphia Eagles, but they’ve reloaded offensively heading into the 2025 season. Kansas City added speed and versatility by drafting WR Jalen Royals and RB Brashard Smith , while also picking up veteran QB Gardner Minshew as a reliable backup to All-Pro QB Patrick Mahomes . With TE Travis Kel

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