Mike Marteny's DraftKings daily fantasy college football lineup picks for the Saturday (9/6/25) main slate in Week 2. His CFB DFS lineup picks and DFS sleepers will help you win.

We have another dozen games on the Saturday main slate on DraftKings. This isn't as loaded as last week's slate, but we still have a couple of good games and some good offenses against terrible defenses.

We have some teams that don't often appear on DFS slates, but at least they are all FBS teams. The price is prohibitive on some of these guys, so I'll be playing most of my lineups with mid-range players.

In this article, I will provide you with my daily fantasy college football lineup picks for the main DraftKings slate on 9/6/25, starting at noon Eastern . I’ll give multiple player suggestions for players

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