Christian McCaffrey’s status for Week 1 just got a little shakier.

The star 49ers running back didn’t practice on Friday due to a calf injury, according to ESPN’s Adam Schefter .

McCaffrey told reporters after practice that the injury was “nothing serious” and that he “plans to play” on Sunday.

“I feel great about where I’m at,” McCaffrey said. “Unfortunately, when you have the injury history that I have, sometimes when you don’t practice things get blown out of proportion.”

pic.twitter.com/SPYnfSLRaM — Vic Tafur (@VicTafur) September 5, 2025

He’s listed as questionable for Sunday’s game against the Seahawks in Seattle.

The news comes one day after McCaffrey suddenly popped up on San Francisco’s injury report .

McCaffrey had been a full participant in 49ers practice as recentl

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