In the only ranked matchup of Week 2, No. 15 Michigan visits No. 18 Oklahoma at 7:30 p.m. ET tonight.

This is just the second ever meeting between these two storied programs. The first one was in the 1976 Orange Bowl, which the Sooners won 14-6 to claim the national championship that year.

Neither of these teams faced much of a test in Week 1. The Wolverines dispatched New Mexico 34-17, while Oklahoma took care of Illinois State 35-3. Both teams were undoubtedly treating those games as tune-ups for this week’s critical showdown.

Let’s break down the matchup and discuss some Michigan vs. Oklahoma predictions and best bets.

Michigan vs. Oklahoma predictions and best bets

Oklahoma -4.5 ( -115 at DraftKings )

Over 44.5 ( -110 at FanDuel )

NOTE : Odds are based on the bes

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