The Arizona Cardinals go on the road to take on the New Orleans Saints in NFL Week 1 action. New Orleans missed the playoffs last year with a 5-12 record. Kellen Moore has taken over as the head coach for the Saints. Arizona also missed out on the postseason as the Cardinals logged a 7-10 record. The all-time series between these franchises is tied 16-16.
Kickoff from Caesars Superdome is set for 1 p.m. ET on Sunday, Sept. 7. Arizona is favored by 6.5 points in the latest Cardinals vs. Saints odds at bet365 Sportsbook, while the over/under for total points scored is 43.5. Before making any Saints vs. Cardinals picks or same-game parlays, be sure to see the Week 1 NFL predictions from SportsLine's proven model and check out the latest NFL odds . Bet on Cardinals vs. Saints at bet365, wh