San Francisco 49ers tight end George Kittle will be placed on injured reserve and miss at least the next four games, ESPN reported Tuesday.
The six-time Pro Bowl selection sustained a hamstring injury in the first half of Sunday's season-opening 17-13 victory over the Seattle Seahawks.
Kittle caught a 5-yard touchdown pass in the first quarter to open the scoring and had four receptions on four targets for 25 yards before exiting.
Wide receiver Jauan Jennings also left the game with a shoulder injury but multiple reports Tuesday said the issue wasn't serious. Jennings is considered questionable for the Week 2 game at New Orleans.
In addition to this Sunday's clash with the Saints, Kittle must sit out Week 3 and Week 4 home games against the Arizona Cardinals and Jacksonville Jaguars, r