Key takeaways:

Between 2013 and 2025, use of non-aspirin antithrombotic therapy declined in total joint arthroplasty.

The use of aspirin was associated with decreased infection rates compared with antithrombotic therapy.

JERSEY CITY, N.J. — Results presented at the Musculoskeletal Infection Society Annual Meeting showed use of aspirin was associated with decreased infection rate after total joint arthroplasty.

“Not only by using aspirin are we making it easier for patients to administer medications for [venous thromboembolism] prophylaxis after hip and knee replacement, it is more tolerated, easier to administer and low cost; does not require insurance authorization and, more importantly, it is associated with lower infection and complication rates,” Vinay K. Aggarwal, MD, associa

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