Recent anal cancer screening guideline developments for HIV patients have been an important step in prevention; however, these recommendations have left grey areas concerning the efficacy and cost-effectiveness of screening, according to a clinical review published in Clinical Infectious Diseases .

“The field of anal cancer prevention among people living with HIV is at an inflection point with promising early data and now delineated clinical guidelines,” the authors, including corresponding author Hayden S. Andrews, M.D., from the University of Texas Southwestern Medical Center, write in the review, published in July 2025. “While celebrating this progress, careful attention is needed for ongoing research evaluating its efficacy and increasing infrastructure to make high-resolution ano

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