The San Francisco 49ers started the 2025 season on a high note. San Francisco defeated Seattle 17-13 on a game-winning touchdown from backup tight end Jake Tonges . But the win came at a cost. George Kittle is already on injured reserve , and now 49ers QB Brock Purdy could miss some time with multiple injuries.

49ers head coach Kyle Shanahan declared on Wednesday that Purdy is “a long shot” to play against the Saints, per NFL Network's Tom Pelissero.

Purdy is dealing with a toe and left shoulder injuries after Week 1's win against the Seahawks.

Purdy was considered day-to-day immediately after Week 1. But now Shanahan says Purdy could miss “multiple weeks” per ESPN's Adam Schefter.

Shanahan originally declared that Purdy's toe is a bigger issue than his shoulder .

“I'd p

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