Will Brock Purdy play in Week 2 for fantasy football? Is Brock Purdy injured or hurt heading into Week 2 of 2025? Read the latest Brock Purdy injury report.

San Francisco 49ers quarterback Brock Purdy (toe/shoulder) played just one game in 2025 before suffering toe and shoulder injuries. The 49ers have a long history of constantly being decimated by injury issues, and this season, they already have three offensive starters who played in Week 1 affected by injury issues.

Purdy, tight end George Kittle (hamstring), and wide receiver Jauan Jennings (shoulder) all are now in danger of missing time, with Kittle already having been placed on injured reserve. He'll miss the next four games, at minimum. Purdy and Jennings' situations are less clear.

It would obviously be a huge blow for S

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