Duke football makes its first road trip of 2025, traveling to New Orleans to take on Tulane on Saturday, Sept. 13 at Yulman Stadium (8 p.m. ET, ESPN2).

The Blue Devils are coming off a 45-19 loss to Illinois, one that was defined by five turnovers and a costly equipment violation penalty that swung momentum. Duke is up against a 2-0 Tulane team, with the Green Wave coming off a 33-31 win over South Alabama.

Saturday will be the sixth meeting between the programs, with Duke holding a 3-2 series edge. The Blue Devils have claimed the last three match-ups, with their last win in 2015 coming in New Orleans. The trip also marks a return for former Tulane quarterback Darian Mensah to Yulman Stadium after transferring to Duke in December 2024.

Here's a prediction for Duke's Week 3 conte

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