Mike's Week 3 college football betting picks against the spread for Thursday, September 11, and Friday, September 12, 2025. Free CFB betting predictions, odds analysis, and ATS picks from RotoBaller.

Week 2 of the 2025 college football season brought some more upsets. South Florida is the darling of the Group of 5 after winning in The Swamp. Two more top 25 teams fell to unranked teams. What does Week 3 have in store? How did we do in Week 2? We'll start off the betting week right with the picks for Thursday and Friday.

Long Island and Bryant join Tarleton and Austin Peay as FCS teams to knock off FBS teams with wins over Eastern Michigan and Massachusetts, respectively. There have been more FCS upsets of FBS teams this year, which is always exciting.

We have another loaded weekend with

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