Perhaps no team in the nation has been as impressive as South Florida to open the 2025 season. The Bulls have stunned Boise State and Florida thus far as Alex Golesh's team now has a legitimate path to the College Football Playoff. USF has another chance to pull off a stunner on Saturday when the Bulls take on Miami in a top-20 matchup. The latest Week 3 college football odds list the Hurricanes as 17.5-point favorites, with the over-under at 57.5. The Canes are 6-1 all-time versus their in-state rival.
Other games with potential early CFP implications include Tennessee vs. Georgia (-3.5), LSU vs. Florida (+7.5) and Texas A&M vs. Notre Dame (-6.5). Conference battles include Arkansas vs. Ole Miss (-7.5) and USC vs. Purdue (+20.5). With dozens of college football lines available, what are