Teams looking to stay perfect meet in non-conference action when the Indiana State Sycamores battle the 22nd-ranked Indiana Hoosiers on Friday night. Indiana State downed Eastern Illinois 38-14 on Saturday, while Indiana cruised past Kennesaw State 56-9. The Sycamores (2-0), who finished tied for sixth in the 1-AA Missouri Valley Football Conference and 4-8 overall, were 0-6 on the road last year. The Hoosiers (2-0), who tied for second at 8-1 and were 11-2 overall in 2024, are 10-0 at home since the start of last season. They are 1-1 to open the season against the spread.

Kickoff from Memorial Stadium in Bloomington, Ind., is set for 6:30 p.m. ET. Indiana leads the all-time series 7-0, last meeting in 2023. Indiana is a 48.5-point favorite in the latest Indiana State vs. Indiana odds

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