The Colorado Buffaloes (1-1) will face the Houston Cougars (2-0) on Friday in the Big 12 opener for both teams. The Buffs recently secured a 31-7 victory over Delaware. Head coach Deion Sanders has appointed sophomore Ryan Staub as the starting quarterback for this game. Meanwhile, Houston aims to extend its winning streak following a 35-9 triumph over Rice, with junior quarterback Conner Weigman leading the team.

The game is scheduled for 7:30 p.m. ET at TDECU Stadium in Houston. Houston is favored by 4.5 points, with the over/under set at 45.5. Before placing bets on the game, check out expert Jimmie Kaylor’s insights on SportsLine.

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