Week 2 features a rematch of last year’s Super Bowl , as the defending champion Philadelphia Eagles head to Missouri to battle the Kansas City Chiefs.

Kansas City opened as the slightest of home favorites, but after some key injuries, suspensions and Week 1 results, the favorite has flipped. Philadelphia has now become the favorite despite being the road team. They look to hand Patrick Mahomes a third straight loss for the first time in his career.

Eagles vs. Chiefs predictions and best bets

Philadelphia Eagles ML -116 at FanDuel Sportsbook

Philadelphia Eagles -1 (-110) at BetMGM Sportsbook

A.J. Brown over 73.5 receiving yards (-111) at DraftKings Sportsbook

Tyquan Thornton longest reception over 16.5 yards (-118) at Caesars Sportsbook

*Note: Odds are based on the best

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