Three police officers were killed and two were injured in a shooting Wednesday in the southern part of Pennsylvania, state police said.

The shooting erupted in the area of North Codorus Township, about 115 miles (185 km) west of Philadelphia, not far from the Maryland line, authorities said.

York Hospital said it was treating two people in serious condition and had enhanced security protocols are in place.

Attorney General Pamela Bondi called the violence against police “a scourge on our society.” She said federal agents were on the scene to support local officers.

Pennsylvania Attorney General Dave Sunday said he was also on the scene. Sunday said on social media he urges “all residents to follow the instructions of local law enforcement” and he is “praying for all involved.”

A local school district issued a shelter-in-place order, though it said schools and students were not involved in the shooting. The order was lifted later in the afternoon. The district said in a statement that authorities “advised us to hold students and staff in our buildings as a precaution while several area roads are closed.”

The medical response unfolded on a rural road in south-central Pennsylvania that winds through an agricultural area with a barn and farm fields.