The No. 24 Notre Dame Fighting Irish (0-2) will be desperate to pick up their first win of the season when they host the Purdue Boilermakers (2-1) in an in-state battle on Saturday afternoon. Notre Dame's College Football Playoff hopes are on thin ice following losses to then-No. 10 Miami and then-No. 16 Texas A&M to open the campaign. Purdue won its first two games of the season against overmatched opponents, but it lost to USC in a 33-17 final last week. Notre Dame has won nine of the last 10 meetings between these teams, including a 66-7 win last year.

Kickoff from Notre Dame Stadium is set for 3:30 p.m. ET on Saturday on NBC. Notre Dame is a 24.5-point favorite in the latest Notre Dame vs. Purdue odds from SportsLine consensus, while the over/under for total points scored is 51.5.

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