The San Francisco 49ers enter Sunday’s divisional matchup against the Arizona Cardinals with quarterback uncertainty dominating the headlines. Brock Purdy, who has been battling shoulder and toe injuries, is officially questionable, but head coach Kyle Shanahan has already indicated it’s “highly unlikely” the starter will take the field. Instead, Mac Jones—who led the Niners to victory in Week 2—will be under center at Levi’s Stadium, with Purdy only available in a backup or emergency capacity if healthy enough to dress.

Despite the quarterback shuffle, San Francisco remains a slight favorite at home. Oddsmakers list the 49ers at -2.5 on the spread and -130 on the moneyline, with Dimers’ predictive model giving them a 60% chance of victory after simulating the matchup 10,000 times. The

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