The San Francisco 49ers, ahead of their Week 3 home opener against the Arizona Cardinals , announced multiple roster moves, chief among them was placing fourth-year offensive lineman Spencer Burford on injured reserve with a knee injury, ESPN's Adam Schefter reported.

Burford, a fourth-round pick in 2022, sustained the injury in the team’s Week 2 game against the New Orleans Saints. He played just five snaps on special teams before exiting.

Head coach Kyle Shanahan had initially described Burford’s situation as day-to-day, but the team confirmed Saturday that surgery may be a possibility. By rule, Burford will now be out of action for at least four games.

In his career, Burford has appeared in 47 games with 29 starts, most of them at right guard. As a rookie in 2022, he started all

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