Researchers from the University of Texas MD Anderson Cancer Center have shown that glucose-fructose mix found in sweet sugary drinks directly fuels metastasis in preclinical models of colorectal cancer (CRC). Their research, published in Nature Metabolism , identified the SORD enzyme, which plays a role in converting sorbitol to fructose, as a key driver of the metastatic spread of CRC.

“Our findings highlight that daily diet matters not only for cancer risk but also for how the disease progresses once it has developed,” said senior author and study leader Jihye Yun, PhD, assistant professor of genetics at MD Anderson. “While these findings need further investigation, they suggest that reducing sugary drinks, targeting SORD, or repurposing statins may benefit patients with colorecta

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