President Donald Trump blasted Tylenol this week, promoting unproven links between the pain reliever and autism and pushing the well-established treatment into another national image crisis.

“Don’t take Tylenol,” Trump instructed pregnant women around a dozen times during a White House news conference. He also urged mothers not to give infants the drug, known by the generic name acetaminophen in the U.S. or paracetamol in other countries.

The attack on Tylenol by the U.S. president was unprecedented but not exactly new territory for one of the world’s most common pain relievers. Tylenol already has faced dozens of lawsuits regarding the autism claim, and it dealt with cyanide poisoning s in the 1980s that led to a product recall.

Some studies have raised the possibility that taking the

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