"I'm not sure who had a weirder 48 hours — me, or the CEO of Tylenol," Jimmy Kimmel joked as he opened his show Tuesday night to a standing ovation after nearly a week away.

In a monologue that turned emotional, the comedian choked up addressing the family of Charlie Kirk, the right-wing activist who was killed Sept. 10.

"I've been hearing a lot about what I need to say and do tonight," he said. "And the truth is, I don't think what I have to say is going to make much of a difference … I have no illusions about changing anyone's mind."

Kimmel said, however, that he wanted to make one thing clear: "It was never my intention to make light of the murder of a young man."

He said he meant it when he posted a message on Instagram sending love to Kirk's family after he was killed. And Kimmel

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