Researchers at the Wellcome Sanger Institute, the University of Cambridge, and the University of Newcastle in the U.K. have mapped human skin fibroblasts as part of the international Human Cell Atlas consortium. Their research revealed several fibroblast subtypes involved in multiple diseases, including acne, psoriasis, rheumatoid arthritis, and inflammatory bowel disease. This presents fibroblasts as potential drug targets for the first time.

Fibroblasts are scaffolding cells in the skin and other organs that are responsible for shaping the architecture and cellular microenvironment of different tissues. They play a role in wound healing, tissue repair, scarring, connective tissue formation, and maintenance of the skin.

Due to their involvement in scarring and inflammation, unders

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