One of the most anticipated weekends on the 2025 college football calendar is upon us.

The headliner comes Saturday night when No. 6 Oregon visits No. 3 Penn State . A potentially season-defining occasion, the clash of Big Ten powers, will test quarterbacks Drew Allar (Penn State) and Dante Moore (Oregon), Nittany Lions coach James Franklin and the Ducks' backbone as they step into the hostile confines of Beaver Stadium in Week 5.

Elsewhere, eyes will fall on a trio of juicy SEC matchups: Alabama - Georgia , Auburn - Texas A &M and Ole Miss - LSU , all of which could hold significant implications for the conference title race and the College Football Playoff field.

Ahead of a series of high-level games, our college football reporters deliver their insights on keys t

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