By Week 4 of the NFL season, patterns emerge among wide receivers and tight ends, but surprises are still possible. Let’s lean into matchups, volume and inefficiencies. Here are your starts, locks and avoids going into Week 4.

Start: Rome Odunze vs. Raiders

Odunze’s matchup with Las Vegas offers big-play potential. Odunze’s combination of size and speed makes him difficult for Vegas corners to handle one-on-one, and the Raiders have been prone to giving up intermediate and vertical completions to physical WRs. Averaging nine targets a game and having scored in every game so far this season, he has a chance to deliver his best fantasy line yet in 2025.

Other WR Locks:

Avoid: Marquise Brown, Chiefs vs. Ravens

Brown’s target share has been inconsistent. If the Chiefs go toward other rout

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