Liverpool, flawless in their Premier League title defence so far this season, will face a serious test when they visit unbeaten Crystal Palace on Saturday.
Arsenal cannot afford another Newcastle nightmare, while Manchester United boss Ruben Amorim is in desperate need of a winning run.
AFP Sport looks at three key talking points ahead of the weekend's action:
Palace pose Liverpool threat
Liverpool have got off to a flyer with seven straight wins in all competitions, but the Premier League leaders will face a stern examination at Selhurst Park.
The Reds, bolstered by their knack for scoring late winners, have marched five points clear after reeling off five successive league victories.
However, Oliver Glasner's Palace are also flying high, in fifth place.
The FA Cup holders are the