Sep 20, 2025; Fort Worth, Texas, USA; TCU Horned Frogs wide receiver Eric McAlister (1) celebrates in front of SMU Mustangs safety Abdul Muhammad (27) after McAlister scores a touchdown during the second half at Amon G. Carter Stadium. Mandatory Credit: Jerome Miron-Imagn Images

Friday night football is back when TCU heads to Arizona State in a huge Big 12 conference game in Tempe. The Horned Frogs have started the season with three straight wins that include victories over North Carolina and SMU.

The Sun Devils, who are coming off a Big 12 championship, are 3-1 on the season. They were shocked by Mississippi State, but bounced back with a win over Baylor last week. They got the win, but it wasn't easy. They needed a last-second field goal to beat the Bears 27-24.

If you're looking to get back in the swing of football season and need some betting advice for Friday's matchup in Tempe, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Stream Arizona State vs. TCU

Arizona State vs. TCU game odds:

All college football odds via BetMGM

  • Spread: NC State -3 (-110), TCU +3 (-110)
  • Money Line: NC State -150, TCU +125
  • Over-Under: Over 55.5 (-105), Under 55.5 (-115)

Arizona State vs. TCU prediction, pick:

The Horned Frogs and Sun Devils both have a good win over a Power Four school, but the Sun Devils are the ones who struggled against a Mississippi State team that was bad last year. The Horned Frogs showed they could win a higher-scoring game when they beat SMU in their last game. The Horned Frogs have looked better so far this season, while the Sun Devils seem to shaky. Take the Horned Frogs in this one to get the upset win.

Prediction: TCU 31, Arizona State 23

Best Bet: TCU +3, Under 55.5

Arizona State vs. TCU channel, start time, streaming:

Time: 9 p.m. ET

TV Channel: FOX

Live Stream: FOX App

Get more betting analysis and predictions at Sportsbook Wire.

Contact/Follow @College_Wire on X and @College_Wires on Threads. Like our page on Facebook to follow ongoing coverage of college sports news, notes, and opinions.

This article originally appeared on College Sports Wire: Arizona State vs. TCU: Week 5 College Football Betting Odds, Prediction, Pick

Reporting by Adam Childs, College Sports Wire / College Sports Wire

USA TODAY Network via Reuters Connect