The San Francisco 49ers take on the AFC South’s Jacksonville Jaguars at Levi’s Stadium on Sunday, Sept. 28 at 1:05 p.m. PDT.

The Niners will be without Nick Bosa for the first time this season after he tore the ACL in his right knee. It’s not clear who will start at quarterback as Brock Purdy practiced last week but remained out with a toe injury, while backup Mac Jones played well in key moments for a second straight week in a win over Arizona.

They’ll also face old friend Arik Armstead, who signed with Jacksonville before last season.

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How to watch on local TV

FOX is broadcasting the game in California; in the Bay Area, tune in to KTVU-TV (channel 2) with an antenna or a cable TV provider. You can also log in to the FOX Sports app or website with your cable TV subscr

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