If you're a fan of college football, the Week 5 schedule is what dreams are made of. Four top-25 matchups are set to unfold on Saturday, including a Big Ten battle featuring No. 3 Penn State hosting No. 6 Oregon at 7:30 p.m. ET. The Ducks are 8-0 in their last eight games on the road, while the Nittany Lions are 10-2 in their previous 12 conference games. According to the latest Week 5 college football odds , the Nittany Lions are favored by 3.5 points at home, while the over/under for total points scored is 53.5. SportsLine's model is backing Oregon, which is 18-1 in its last 19 games overall, to cover the spread in 55% of simulations at Penn State.

The model is also backing Notre Dame (-4.5) to cover the spread at Arkansas, while the Over (60.5) hits 61% of the time in USC vs. Illino

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