Dr. Jane Goodall, one of the world’s most beloved animal behaviorists and a pioneer in primatology has died at the age of 91, the Jane Goodall Institute confirmed Wednesday.

The British scientist, best known for her groundbreaking work with chimpanzees in Tanzania’s Gombe Stream National Park, passed away of natural causes while on a speaking tour in California.

“Dr. Goodall’s discoveries as an ethologist revolutionized science, and she was a tireless advocate for the protection and restoration of our natural world,” the institutde said in a statement.

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