San Francisco 49ers quarterback Brock Purdy is officially out for "Thursday Night Football" against the Los Angeles Rams with a toe injury. Mac Jones is expected to start in Purdy's place.

Purdy already missed two games -- Week 2 vs. the New Orleans Saints and Week 3 vs. the Arizona Cardinals -- due to his turf toe injury, but he returned in Week 4 against the Jacksonville Jaguars . However, Purdy said he felt soreness in his toe after the Jaguars game, a 26-21 loss. Purdy went 22 of 28 for 309 yards with two touchdowns and two interceptions in last week's matchup.

Purdy hoped to play Thursday despite sitting out of practice on Monday or Tuesday.

"If I can play this game, I want to play," Purdy said, via ESPN . "Obviously, I want to get right and get healthy and everyt

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