San Francisco 49ers quarterback Brock Purdy will miss Thursday night's showdown against the host Los Angeles Rams due to his turf toe injury.

Purdy missed practice Wednesday for the third straight day.

This will mark Purdy's third absence in four games due to the injury. He was initially hurt during a Week 1 contest against the Seattle Seahawks and aggravated the injury during last week's 26-21 home loss against the Jacksonville Jaguars.

Mac Jones will draw the start for the 49ers (3-1). He started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

Receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive end Robert Beal Jr. (ankle) also were declared ou

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