At first glance, tonight's clash between NFC West rivals San Francisco (3-1) and the Rams (3-1) looks an evenly matched battle between two of the top teams in the NFC.

The Rams' only loss came to the Eagles in a game they led big in Week 3, while the 49ers entered their Week 4 matchup with the Jaguars at 3-0.

But L.A. is heavily favored tonight, as the 49ers are without a number of key players, especially offensively. We'll dive into the latest 49ers vs. Rams injury news and how the former's mounting injuries affected the betting odds for this game, but with Brock Purdy among several top offensive players out for SF, oddsmakers expect L.A. to roll.

Will the Rams be too much for the shorthanded Niners, or will Mac Jones improve to 3-0 in relief of Purdy this year?

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