This image shows three brain cells with the faulty protein that causes Huntington’s disease. The bright yellow cell in the middle has built up a clump of this protein inside it. The blue spots in the background are the cell nuclei of nearby, unaffected brain cells. Dr. Steven Finkbeiner, Gladstone Institute of Neurological Disease, The Taube-Koret Center for Huntington's Disease Research, and the University of California, San Francisco

New data from a gene therapy trial provide the first credible evidence that the progression of Huntington’s disease may be slowed by a single, targeted intervention. Huntington’s is a rare but devastating genetic illness caused by a single inherited mutation. If you carry the defective gene, you will almost certainly develop the disease, often in mid-

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