A new systematic review and meta-analysis published in the International Forum of Allergy & Rhinology revealed a striking connection between rhinosinusitis, and the development of systemic rheumatic diseases. The findings suggest that chronic sinus inflammation may not only affect breathing and quality of life but could also unmask hidden autoimmune conditions.

This study included data from 9 international studies and examined whether individuals with rhinosinusitis face higher odds of developing conditions like rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and ankylosing spondylitis. By analyzing both prevalence and risk, this study applied random-effects models to ensure statistical robustness.

The results revealed a strong association between chronic rhinosinusitis

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