Week 6 action continues with a Big 12 matchup between two teams looking to reverse rough starts to conference play.

The Colorado Buffaloes travel to Fort Worth to take on the TCU Horned Frogs as both teams search for their first Big 12 win. The Buffaloes have had some growing pains without Shedeur Sanders and Travis Hunter, and they've already suffered conference losses to Houston and BYU.

The Frogs, meanwhile, had a nice start to the season at 3-0 after demolishing Bill Belichick's North Carolina in Week 1, but they squandered a 17-0 lead in last week's Big 12 opener against defending champion Arizona State, losing 27-24.

Stream TCU vs. Colorado

If you are looking for betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

TCU vs. Colorado game odds

All college football odds via BetMGM

  • Spread: TCU -13.5 (-115), Colorado +13.5 (-105)
  • Money line: TCU -550, Colorado +400
  • Over/Under: Over 57.5 (-110), Under 57.5 (-110)

TCU vs. Colorado prediction, pick:

TCU's offense has been great to start the season, but it met its match against Arizona State with quarterback Josh Hoover tossing a pair of interceptions. Colorado seems to be better with Kaidon Salter back in the starting lineup, and while I think the Horned Frogs probably win this game at home, this line seems a bit too big for my liking.

Prediction: TCU 31, Colorado 21

Best Bet: Colorado +13.5, Under 57.5

TCU vs. Colorado channel, start time, streaming:

Time: 7:30 p.m. ET

TV Channel: Fox

Live Stream: Fox Sports App

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: TCU vs. Colorado: Week 6 college football betting odds, prediction, pick

Reporting by Tyler Nettuno, College Sports Wire / College Sports Wire

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