The Las Vegas Raiders (1-3) travel to play the Indianapolis Colts (3-1) in an AFC showdown in Week 5. Geno Smith and the Raiders have now lost three straight games. Last week, the Chicago Bears narrowly beat Las Vegas, 25-24. Likewise, Daniel Jones and the Colts are coming off their first loss. In Week 4, Indianapolis fell 27-20 to the Los Angeles Rams.

Kickoff from Lucas Oil Stadium is set for 1 p.m. ET. Indianapolis is a 7-point favorite in the latest Raiders vs. Colts odds from SportsLine consensus, while the over/under for total points scored is 48. The Colts are -325 money line favorites (risk $325 to win $100), while the Raiders are +256 underdogs. Before making any Raiders vs. Colts picks, make sure you check out the picks from the SportsLine Projection Model.

Click here to bet R

See Full Page