Fantasy football start em, sit em MNF lineups advice for Chiefs vs. Jaguars on Monday Night Football in Week 5 (2025). NFL matchups analysis and MNF starts/sits.

The final game of the Week 5 NFL slate pits two potential playoff teams against each other in Duval County. The Jaguars are out to a 3-1 start, and a win over Patrick Mahomes and the Chiefs could establish them as a real postseason threat. There are also several key players in this game on the start 'em, sit 'em bubble for fantasy football, so many matchups will be decided on Monday night.

Below, read about the fantasy football outlooks for key players like Xavier Worthy , Brian Thomas Jr. , Travis Hunter , Brenton Strange , Travis Kelce , Kareem Hunt , and more. Which Chiefs and Jaguars players should you start or

See Full Page