The Detroit Lions are back in action in Week 5 of the 2025 NFL season and for the third time this year, they'll face an AFC North team.

It's Lions vs. Cincinnati Bengals at Paycor Stadium (4:25 p.m., Fox, streaming on Fubo with a free trial ), where the Bengals will be without star quarterback Joe Burrow and the Lions are without starting left tackle Taylor Decker . That forces second-year tackle Gio Manu to make his first career NFL start.

The Lions showed in a Week 4 domination of the Cleveland Browns that they're capable of not messing around against inferior opponents, and this game against the Bengals will be another test of their ability to focus on the here and now. In Week 6, the Lions will travel to Kansas City to face the Chiefs and Patrick Mahomes. Watch Lions-

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