STOCKHOLM -- A west suburban man is among the three winners of the 2025 Nobel Prize in medicine for work on peripheral immune tolerance.

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi won the Nobel Prize in medicine on Monday for their discoveries concerning peripheral immune tolerance.

Ramsdell was born in Elmhurst, Illinios. He is a scientific adviser for Sonoma Biotherapeutics in San Francisco.

Brunkow is a senior program manager at the Institute for Systems Biology in Seattle. Sakaguchi is a distinguished professor at the Immunology Frontier Research Center at Osaka University in Japan.

Thomas Perlmann, Secretary-General of the Nobel Committee, said he was only able to reach Sakaguchi by phone Monday morning. He left voicemails for Brunkow and Ramsdell.

Peripheral immune tol

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