Kaiser Permanente is laying off hundreds of workers across California, further deepening tensions with its union of 31,000 nurses that is preparing a five-day strike beginning next week.

In an Oct. 6 letter filed with the state’s Employment Development Department, Kaiser’s Human Resources Director Christine Neubauer said that the Oakland-based health care provider began notifying 216 workers of their layoffs starting Sept. 17.

The bulk of layoffs — 184 people — are coming to the Bay Area cities of Oakland, Redwood City, San Leandro, Pleasanton and Walnut Creek.

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The remaining layoffs — 32 — are taking place in Corona, Downey, Los Angeles, Pasadena and San Diego.

She wrote that Kaiser anticipates the termination dates for employees will come after a 60-day notification

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