The No. 15 Michigan Wolverines (4-1, 2-0 Big Ten) and USC Trojans (4-1, 2-1) square off in a Big Ten showdown Saturday evening. Kickoff from Los Angeles Memorial Coliseum in Los Angeles is set for 7:30 p.m. ET (NBC). Let's analyze BetMGM Sportsbook's NCAA football odds around the Michigan vs. USC odds and make our expert college football picks and predictions for the best bets.

The Wolverines beat the Wisconsin Badgers 24-10 Saturday, closing as a 17.5-point home favorite. The Under 43 hit. RB Justice Haynes led the way with 117 yards and 2 scores on 19 carries. Michigan has rattled off 3 straight wins yet is just 2-3 against the spread (ATS) on the season.

The Trojans, who did get votes to crack the top 25, lost to the Illinois Fighting Illini 34-32 Sept. 27 in Week 5

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