The San Francisco 49ers have overcome numerous injuries to start the season 4-1. A banged up Mac Jones is expected to lead San Francisco’s offense again in Week 6 with Brock Purdy ruled out . And the 49ers are playing without star pass rusher Nick Bosa, who suffered a season-ending ACL tear in Week 3.

However, the compromised club received some positive injury news on Saturday. Malik Mustapha was activated from the physically unable to perform (PUP) list, per ESPN's Adam Schefter. The promising second-year safety should make his season debut against the Tampa Bay Buccaneers in Week 6.

49ers anticipate Malik Mustapha return in Week 6

Mustapha had a strong rookie campaign for the 49ers. The former fourth-round draft pick recorded 72 total tackles (32 solo) with an interception and f

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