When Colts quarterback Andrew Luck abruptly retired six years ago, Jacoby Brissett was thrust into the starting role. Now, Brissett may be starting again in Indianapolis, when the Cardinals face the Colts on Sunday.

Multiple reports indicate that, at a minimum, the Cardinals are preparing to start Brissett in place of Kyler Murray. ESPN states it more strongly, with a report that Brissett is expected to start . NFL Media reports that the Cardinals are leaving the door open for Murray to play.

Via Ian Rapoport of NFL Media, Murray has a mid-foot sprain — and it’s possible that Murray will miss more than Sunday’s game.

Brissett has started 53 games since entering the league as a third-round pick of the Patriots in 2016. He has played for the Patriots, Colts, Dolphins, Browns,

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