The San Francisco 49ers (4-1) visit the Tampa Bay Buccaneers (4-1) Sunday at Raymond James Stadium in Tampa, Florida. Kickoff is scheduled for 4:25 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Buccaneers odds and make our expert NFL picks and predictions for the best bets.

San Francisco beat the LA Rams last week 26-23 in overtime, covering as an 8.5-road underdog as the Over (44) hit. QB Mac Jones threw for 342 yards and 2 TDs, with WR Kendrick Bourne the top target (10 receptions, 142 yards). The 49ers, who never trailed, rushed for just 74 yards, averaging 2.24 yards per carry in the upset win.

Tampa Bay outlasted the Seattle Seahawks 38-35 last week in an offensive shootout, covering as a 3.5-point road underdog with the Over (44.5)

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