• Needle-free devices like TAP and Tasso offer painless blood collection, a benefit for the squeamish. • These tests face challenges with sample size and accuracy compared to traditional methods. • This article is part of "Transforming Treatments," a series on medical innovations that save time, money, or discomfort.

Dr. Zev Williams, the chief of reproductive endocrinology and infertility at Columbia University Irving Medical Center, clearly remembers a particular patient who walked into his clinic. She was only 16 years old, but had chosen to freeze her eggs before undergoing fertility-threatening treatment for severe sickle cell disease. Her condition had left her blood vessels with extensive scarring, which made the frequent blood draws required for fertility preservation highly d

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