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Basketball is back as the Knicks host the Cleveland Cavaliers Wednesday night at Madison Square Garden to kickstart their 2025-26 NBA season.

Jalen Brunson, Karl-Anthony Towns, and company start their 82-game quest against a familiar foe in Donovan Mitchell and the Cavs.

Mike Brown’s head coaching tenure in New York begins as the Knicks officially take the floor for the first time in the post-Tom Thibodeau era.

The Blue and Orange are -145 favorites ahead of the game, garnering 57 percent of the bets wagered on the moneyline, per BetMGM data.

Tipoff for the Knicks’ home opener is set for 7:00 p.m. ET on ESPN.

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