The Iowa Lottery offers several draw games for those aiming to win big with rewards ranging from $1,000 to millions. The most an Iowan has ever won from playing the lottery was $343 million in 2018 off the Powerball.

Don’t miss out on the winnings. Here’s a look at Tuesday, Oct. 21, 2025, winning numbers for each game:

Winning Mega Millions numbers from Oct. 21 drawing

02-18-27-34-59, Mega Ball: 18

Check Mega Millions payouts and previous drawings here.

Winning Pick-3 numbers from Oct. 21 drawing

Midday: 1-4-2

Evening: 5-4-8

Check Pick-3 payouts and previous drawings here.

Winning Pick-4 numbers from Oct. 21 drawing

Midday: 5-2-9-2

Evening: 5-2-7-9

Check Pick-4 payouts and previous drawings here.

Winning Lucky For Life numbers from Oct. 21 drawing

08-09-15-31-32, Lucky Ball

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