LEXINGTON, Ky. , Oct. 21, 2025 /PRNewswire/ -- What if the same medication that helps you lose weight could also turn back your biological clock? In a landmark 32-week, double-blind, placebo-controlled trial, researchers found that semaglutide (the active ingredient in Ozempic®) reversed biological age by an average of 3.1 years , slowed the pace of aging by nearly 9% , and demonstrated organ-specific rejuvenation . These findings mark the first time a GLP-1 receptor agonist has shown age-reversal effects at the molecular level in humans.

"This trial is the first to show that a GLP-1 drug can improve some of the epigenetic biological aging clocks which have been shown to be the most predictive of aging and health outcomes," said Ryan Smith , Founder & Director of Research

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